Diphtheria-, Tetanus-, Poliomyelitis vaccine

Product

Diphtheria-, Tetanus-, Poliomyelitis vaccine


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Diphtheria-, Tetanus-, Poliomyelitis vaccine


Product

Diphtheria-, Tetanus-, Poliomyelitis vaccine


Combination vaccine
This vaccine is intended to provide active immunization against diphtheria, tetanus, and poliomyelitis.1
Diphtheria, Tetanus, Poliomyelitis vaccine (DTIPV) is indicated for use in children from 5 years of age, adolescents, and adults for primary vaccination and for booster vaccination after the primary series against diphtheria, tetanus, and poliomyelitis.1 Vaccination with the diphtheria and tetanus components of the vaccine results in the production of toxinneutralizing antibodies and the stimulation of immunological memory. Vaccination with the polio component results in humoral immunity and immunological memory.1
Link to HCP info Dutch Marketing Authorisation
Link to package leaflet Dutch Marketing Authorisation

Combination

Diphtheria
Diphtheria is an infectious illness caused by bacteria that produce a harmful toxin.
It spreads easily from person to person, usually when someone who is infected coughs or sneezes. Some people may carry the bacteria without feeling sick themselves, but they can still pass it on to others. Others may develop mild symptoms, while some can develop severe disease, complications, or even life‑threatening illness.2


Anyone can get diphtheria, but it used to be most common in children who were not vaccinated.2
The toxin produced by the bacteria can damage the throat and airways and can also spread to other parts of the body. Typical symptoms include fever, a sore throat, and swollen glands in the neck.2

Tetanus
Tetanus is a serious infection caused by germs (called spores) from the bacteria Clostridium tetani.
These spores are commonly found in the environment—especially in soil, dust, and animal or human waste. They can also be present on the skin and on metal objects like rusty nails, needles, or wire. Because these spores are very tough, they can survive in the environment for many years.3
Anyone can get tetanus, but it is especially dangerous for newborn babies and pregnant women who have not received enough vaccinations that protect against tetanus.
Tetanus is still a significant health problem in many parts of the world—particularly in areas where vaccination rates are low or where births take place in unclean conditions.3

Poliomyelitis
Polio is a serious and very contagious disease caused by a virus. It can affect the nervous system and sometimes cause paralysis very quickly. The virus spreads mainly when tiny bits of stool from an infected person get into another person's mouth, often through unwashed hands or sometimes through contaminated food or water. Once inside the body, the virus grows in the intestines.4

Early symptoms can feel like the flu and may include fever, tiredness, headache, vomiting, stiff neck and pain in the arms or legs. In rare cases, about 1 in 200 infections, polio can cause permanent paralysis, usually of the legs. Among those who develop paralysis, 5–10% may die if the muscles used for breathing become affected.4
Polio mostly affects young children under 5 years old, but anyone who is not vaccinated—no matter their age—can get the disease.
There is no cure for polio. The only effective protection is vaccination.4

Sources

1. Summary of Product Characteristics Diphtheria-, Tetanus-, Poliomyelitis vaccine, November 2024

2. WHO Factsheet Diphtheria, https://www.who.int/news-room/fact-sheets/detail/diphtheria, accessed on 11 January 2026

3. WHO Factsheet Tetanus, https://www.who.int/news-room/fact-sheets/detail/tetanus, accessed on 11 January 2026

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